PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge
نویسندگان
چکیده
منابع مشابه
A novel minimal model to describe NEFA kinetics following an intravenous glucose challenge.
Dynamics of nonesterified fatty acid (NEFA) metabolism in humans requires quantification if we are to understand the etiology of such diseases as type 1 and 2 diabetes, as well as metabolic syndrome and obesity, or if we are to elucidate the mechanism of action of various interventions. We present a new compartmental model that employs the pattern of plasma glucose concentrations in healthy you...
متن کاملInnovative Methodology A novel minimal model to describe NEFA kinetics following an intravenous glucose challenge
Boston RC, Moate PJ. A novel minimal model to describe NEFA kinetics following an intravenous glucose challenge. Am J Physiol Regul Integr Comp Physiol 294: R1140–R1147, 2008. First published January 30, 2008; doi:10.1152/ajpregu.00749.2007.—Dynamics of nonesterified fatty acid (NEFA) metabolism in humans requires quantification if we are to understand the etiology of such diseases as type 1 an...
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The role of inflammation in colorectal carcinogenesis may differ according to individuals' genetic variations. Therefore, we investigated whether genetic susceptibility alters the association between inflammatory potential of diet and the risk of colorectal cancer within the Korean population. We genotyped four polymorphisms in four genes (IL1B, TNF, PPARG, and PPARGC1A) and calculated the diet...
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Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. We sought to determine whether this association was explained by differences in fasting non-esterified fatty acid (NEFA) levels and/or NEFA suppression after oral glucose loading. Materials and Methods. We performed a cross-sectional analysi...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2007
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-006-0580-1